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Purple KushÂ can also be effective as a medication. Its powerful sedative effects can blunt some symptoms of anxiety and depression. It can also be surprisingly effective in relieving pain — both situational, like the aches that set in after a workout, or chronic, like the nerve-related pain that comes with cancer or fibromyalgia. In large enough doses, Purple Kush is also a great way to treat entrenched insomnia. The strainâ€™s high is said to have an average duration of 2 to 3 hours.